
We are seeking a motivated postdoctoral Research Associate to join a translational research programme funded by the Medical Research Council. Based at the University of Manchester, the project focuses on improving molecular diagnosis and understanding disease mechanisms in inherited eye diseases using advanced genomic technologies, long-read sequencing, and functional assays.
The successful applicant will independently lead laboratory work, including genomic, molecular, and cell biology experiments. Experience in variant characterisation, RNA analysis, or functional assays (e.g. splicing reporters, luciferase assays, or NMD inhibition) is essential. We particularly welcome applicants with broader biological expertise relevant to modelling disease mechanisms or therapeutic development, which may include the use of stem cell-derived systems (e.g. iPSC models), tissue models, or in vivo approaches. Familiarity with long-read sequencing and bioinformatics interpretation is also desirable.
This position offers the opportunity to join a collaborative, interdisciplinary team working across clinical, computational, and experimental domains.
What you will get in return:
As an equal opportunities employer we welcome applicants from all sections of the community regardless of age, sex, gender (or gender identity), ethnicity, disability, sexual orientation and transgender status. All appointments are made on merit.
Our University is positive about flexible working – you can find out more here
Hybrid working arrangements may be considered.
Please note that we are unable to respond to enquiries, accept CVs or applications from Recruitment Agencies.
Any recruitment enquiries from recruitment agencies should be directed to People.Recruitment@manchester.ac.uk. Any CV’s submitted by a recruitment agency will be considered a gift.
Enquiries about the vacancy, shortlisting and interviews:
Name: Dr Siying Lin
Email: siying.lin@manchester.ac.uk
General enquiries:
Email: People.recruitment@manchester.ac.uk
Technical support:
https://jobseekersupport.jobtrain.co.uk/support/home
This vacancy will close for applications at midnight on the closing date.
Please see the link below for the Further Particulars document which contains the person specification criteria.