The Herbert group seek two highly motivated scientists to join us studying the cellular basis of complex tissue formation, in particular the role cell shape and geometry play in directing cell mechanics, signalling and behaviour driving tissue morphogenesis.
Our latest Wellcome Trust-funded research aims to define:
(1) Novel mechanisms of cell shape control: Can subcellular targeting and translation of mRNAs drive local cell shape remodelling in cell migration? Does interphase cell geometry reshape the biomechanics of mitosis to induce asymmetric cell division?
(2) New roles for cell shape in defining cell function: Can post-mitotic cell geometry direct differential daughter cell fate? Does local cell shape remodelling polarise cells?
We employ a sophisticated multidisciplinary approach to investigate tissue formation, encompassing in-vivo genetic or live-imaging studies in zebrafish, in-vitro ‘omics’ or micropatterning approaches in human cells, in-silico modelling methods, CRIPSR gene-editing, and aim to extend these efforts to include optogenetic tools. Tissue models of interest include angiogenesis, neural crest, neural progenitors and cancer.
PhD-level experience in these areas is ideal, but applicants with similar interests and a strong track record in other cell and developmental biology fields are also actively encouraged. The position is available from 1st October 2020 and is tenable for at least 4.5 years. To learn more about the Herbert group, visit www.herbertlab.com.
The School is committed to promoting equality and diversity, including the Athena SWAN charter for promoting women’s careers in STEMM subjects (science, technology, engineering, mathematics and medicine) in higher education. The School holds a Bronze Awardfor their commitment to the representation of women in the workplace and we particularly welcome applications from women for this post. All appointments will be made on merit. For further information, please visit:
https://www.bmh.manchester.ac.uk/about/equality/
Please note that we are unable to respond to enquiries,accept CVs or applicationsfrom Recruitment Agencies.
Name: Dr. Shane Herbert
Email: shane.herbert@manchester.ac.uk
Tel: 0161 275 1140
Email: hrservices@manchester.ac.uk
Email: universityofmanchester@helpmeapply.co.uk
Tel: 0161 850 2004
