Cells survive changes in their environment by regulating signalling downstream of growth factors that activate Receptor Tyrosine Kinases (RTKs), and stress responses to factors like nutrient deprivation, hypoxia, and changes in the mechanical forces. The ability of cells to integrate growth and stress signals underpins health and is compromised in diseases, including breast cancer. This project will uncover the molecular basis of the interplay between RTK and stress responses using omics methods and functional assays in two- and three-dimensional (3D) breast cancer models.
The position provides the opportunity to develop skills in omics and cellular assays within a well-resourced, young, and ambitious team. Holding a PhD in relevant biomedical disciplines, having a publication track-record, having extensive knowledge and proven experience in molecular and cell biology (3D culture) and biochemistry, being enthusiast and self-motivated are essentials. Knowledge of metabolism is desirable.
As this role involves research at a postgraduate level, applicants who are not an EEA national or a national of an exempt country and who will require sponsorship under the Skilled Worker route of the UK Visas and Immigration’s (UKVI) Points Based System in order to take up the role, will be required to apply for an Academic Technology Approval Scheme (ATAS) Certificate and will need to obtain this prior to making any official visa application UKVI
The School is strongly committed to promoting equality and diversity, including the Athena SWAN charter for gender equality in higher education. The School holds a Silver Award which recognises their good practice in relation to gender; including flexible working arrangements, family-friendly policies, and support to allow staff achieve a good work-life balance. We particularly welcome applications from women for this post. All appointment will be made on merit. For further information, please visit: https://www.bmh.manchester.ac.uk/about/equality/
Please note that we are unable to respond to enquiries, accept CVs or applications from Recruitment Agencies.
Enquiries about the vacancy, shortlisting and interviews:
Name: Chiara Francavilla
Name: Michael P. Smith
This vacancy will close for applications at midnight on the closing date.
Please see the link below for the Further Particulars document which contains the person specification criteria.