We are recruiting an ambitious, self-motivated and experimentally talented Research Associate to join us in understanding the regulation and role of biological oscillations in cell state transitions during zebrafish neurogenesis. The specific aims of the project are to understand how oscillatory gene expression is generated and its functional importance of cell state transitions at the tissue level. We will interrogate the relative contribution of protein stability, using live imaging at single cell level to visualise protein dynamics. Parameters governing these processes will be quantitated and used to inform realistic computational models, in collaboration with theoreticians in the lab. To understand the functional importance of oscillations, we will develop and implement methods to manipulate them.
The post is funded by the Wellcome Trust and is available from 1 September 2022, with some flexibility, on a full-time basis, fixed term for three years. Candidates must already hold a PhD or expect to shortly in a Biological discipline and have at least one first author publication, in press or in preparation.
The successful candidate will have extensive experience in using zebrafish as a model system, live tissue confocal microscopy, molecular imaging at the single cell level in time series and image analysis in Zebrafish. Excellent technical skills in molecular biology, including CRISPR/Cas9 editing, and biochemistry, including assays of protein stability are essential.
The School/Department is strongly committed to promoting equality and diversity, including the Athena SWAN charter for gender equality in higher education. The School/Department holds a Silver Award which recognizes their good practice in relation to gender; including flexible working arrangements, family-friendly policies, and support to allow staff achieve a good work-life balance. We particularly welcome applications from women for this post. All appointment will be made on merit. For further information, please visit:
https://www.bmh.manchester.ac.uk/about/equality/
Our University is positive about flexible working – you can find out more here
Blended working arrangements may be considered
Please note that we are unable to respond to enquiries, accept CVs or applications from Recruitment Agencies.
Enquiries about the vacancy, shortlisting, and interviews:
Name: Professor Nancy Papalopulu
Email: nancy.papalopulu@manchester.ac.uk
General enquiries:
Email: People-od.operations@manchester.ac.uk
Technical support:
https://jobseekersupport.jobtrain.co.uk/support/home
This vacancy will close for applications at midnight on the closing date.
Please see the link below for the Further Particulars document which contains the person specification criteria.
