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Research Associate (Klotho)
Oxford Road, Manchester

Job reference: BM&H-14076

Location: Oxford Road, Manchester

Closing date (DD/MM/YYYY): 08/07/2019

Salary: £32,236 to £35,211 per annum (according to relevant experience)

Employment type: Fixed Term

Department: Biology, Medicine & Health

Division: Neuroscience & Experimental Psychology

Hours per week: Full Time

Contract Duration: 1 September 2019 until 31 August 2022

The integrated structure of our Faculty enables a truly translational approach to biology, medicine and health - from pure discovery science through to clinical application and patient care. It also encourages collaborative working, enabling staff to deliver innovative, world-leading research that has a very real and positive impact on people’s lives, as well as high-quality education and training to over 11,000 undergraduate and postgraduate students.


Ageing is the main risk factor for cognitive decline. This project will focus on the anti-ageing protein, klotho, which enhances the function of nerve cells, particularly the changes in synapses that are required for learning and memory. These cognitive-enhancing properties of klotho are mediated by klotho interacting with an unknown receptor on the surface of nerve cells. The aim of this project is to identify and characterise the receptor for klotho. The information obtained during this project will provide new opportunities for cognitive-enhancing strategies to combat age-related cognitive dysfunction.


You will have BSc (hons) and hold a PhD in biochemistry, cell biology, molecular biology, neuroscience or a related discipline. You will have extensive and up-to-date theoretical and practical knowledge in proteomics, protein purification and characterisation, and extensive experience in mammalian cell culture and/or protein identification.


This full time post is available from 1 September 2019 for 3 years.


The School is strongly committed to promoting equality and diversity, including the Athena SWAN charter for gender equality in higher education. The School holds a Silver Award which recognises their good practice in relation to gender; including flexible working arrangements, family-friendly policies, and support to allow staff achieve a good work-life balance. We particularly welcome applications from women for this post. All appointment will be made on merit. For further information, please visit:


Please note that we are unable to respond to enquiries, accept CVs or applications from Recruitment Agencies


Enquiries about vacancy shortlisting and interviews:

Name: Professor Nigel Hooper


Tel: 0161 306 5765

Technical support:


Tel:      0161 850 2004

General enquiries:


Tel:      0161 275 4499


This vacancy will close for applications at midnight on the closing date

Further Particulars and Job Description


The closing date for this job has now passed.