Applications are invited for a post-doctoral research associate to develop new mathematical and computational models of the collagen secretory pathway. The successful candidate will join a team of researchers in Manchester and Bristol investigating how cells build and repair collagen-rich tissues in health and during wound repair. This is a full-time appointment starting on 1st January 2020, or as soon as possible thereafter, and is funded for five years through a UKRI-BBSRC Strategic Longer/Larger (sLoLa) award. The successful applicant will have opportunities for secondment at the University of Bristol during the programme.
The project will involve the development of a set of models at different scales, and their integration into an integrative multiscale model, that quantitatively predicts how a collagen-secreting cell responds to external stimuli (including tissue damage leading to wound healing) to maintain collagen homeostasis. Models will incorporate biochemical and mechanical signals and their spatiotemporal interactions, and will address the collagen secretory pathway, the circadian clock, and the matrix in young and old tissue and in wounds. Models will be informed by information gathered from the partner laboratories in Manchester and Bristol, and the applicant will be closely involved in the design and interpretation of experiments. The project offers an outstanding opportunity for an ambitious and versatile mathematical biologist to gain broad experience of developing and analysing new mathematical models in a highly collaborative multidisciplinary environment.
The successful applicant will be based in the group of Prof. Oliver Jensen (primary supervisor, Department of Mathematics) and work closely on data collection across the collaborating laboratories in the Faculty of Biology, Medicine & Health, University of Manchester and at the University of Bristol.
The successful candidate will have a Ph.D. degree (or equivalent) in applied mathematics, theoretical biophysics or a closely related area. They will have experience of modelling practical applications in physics, engineering or biology and skills in mathematical modelling, computational simulation and analysis of data (including, ideally, image analysis).
As an equal opportunities employer we welcome applicants from all sections of the community regardless of gender, ethnicity, disability, sexual orientation and transgender status. All appointments are made on merit.
Please note that we are unable to respond to enquiries, accept CVs or applications from Recruitment Agencies
Enquiries about vacancy shortlisting and interviews:
Name: Oliver Jensen
Tel: 0161 850 2004
Tel: 0161 275 4499
This vacancy will close for applications at midnight on the closing date
Further Particulars and Job Description